RINGOLACT
Lactated Ringer’s Injection U.S.P.
Therapeutic Class
- Isotonic crystalloid solution.
- Physiologic electrolyte solution.
Description and Composition
a:2:{s:7:"English";s:469:"A clear, colorless solution, each 1000 ml. of which contains:
Calcium Chloride 2H2O |
0.2 grams |
Potassium Chloride |
0.3 grams |
Sodium Chloride |
6.0 grams |
Sodium Lactate |
3.1 grams |
Water for Injections |
q.s. |
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Indications
- Hypovolemic states including dehydration and hemorrhage. Indicated as the initial therapy for rehydration in severe diarrhea and vomiting. Also recommended by the World Health Organization for rehydration in severe dehydration due to diarrhea in patients of all age groups.
- Trauma
- Burns
- Also indicated for the prevention and replenishment of extracellular fluid before, during and after surgery.
- Environmental emergencies such as severe perspiration leading to dehydration and heat illness.
- As a vehicle for Oxytocin injection, for the induction of labor or abortion.
- Can be used in children and neonates for keeping the vein open.
Pharmacological Effects
a:2:{s:7:"English";s:1387:"
- Ringer’s Injection has an electrolyte composition and concentration quite similar to that of the extracellular fluid.
- Even large volumes of infusion of Ringer’s Lactate do not easily cause sodium excess and hyperchloremic acidosis.
- It expands circulating blood volume by approximating the fluid and electrolyte composition of the blood.
- Provides the following electrolytes in each liter of fluid:
Sodium |
130 mEq. |
Chloride |
108.7 mEq. |
Potassium |
4 mEq. |
Calcium |
2.7 mEq. |
Bicarbonate(as Lactate) |
28 mEq. |
- Lactate is metabolized by the liver and converted to bicarbonate. One mole of lactate is metabolized in the body to produce one mole of bicarbonate. Therefore its administration has the same effect as that of bicarbonate.
- The presence of lactate not only eliminates any chances of dilutional acidosis, but also aids in the correction of mild acidosis.
- The infusion of Ringer’s Lactate does not induce hypokalemia and hypocalcemia as compared to normal saline.
- The pH range is 6.0 - 7.5.
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